In a new study, published in the new issue of the American Journal of Clinical Nutrition, data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study indicates that blood levels of selenium may not impact on the risk of prostate cancer.
The researchers, led by Naomi Allen from the University of Oxford, performed a nested case-control study with 959 men with incident prostate cancer and 1,059 healthy men who acted as the controls for comparison.
The concentration of selenium in the blood was not associated with the risk of developing prostate cancer. These null associations were also observed when the researchers accounted for the stage or grade of disease, and for the smoking status of the disease.
"Plasma selenium concentration was not associated with prostate cancer risk in this large cohort of European men,” concluded Allen and her co-workers.
Sources: Cancer Prevention Research
December 2008, doi:10.1158/1940-6207.CAPR-08-0046
"Selenium and Risk of Bladder Cancer: A Population-Based Case-Control Study"
Authors: K. Wallace, K.T. Kelsey, A. Schned, J.S. Morris, A.S. Andrew, M.R. Karagas
American Journal of Clinical Nutrition
December 2008, Volume 88, Pages 1567-1575
"Plasma selenium concentration and prostate cancer risk: results from the European Prospective
Investigation into Cancer and Nutrition (EPIC)"
Authors: N.E. Allen, P.N. Appleby, A.W. Roddam, A. Tjonneland et al.